CLINICAL SCIENCES Magnetic Resonance Imaging of Immune Cells in Inflammation of Central Nervous System
نویسندگان
چکیده
Results. USPIOs covalently attached to antibodies affected the contrast in MRM scan, and their accumulation on cells manifested as signal weakening in T2*-weighted images or signal enhancement in T1-weighted images. With this method applied in the experimental autoimmune encephalomyelitis (EAE) murine multiple sclerosis (MS) model, CNS-infiltrating CD4 T cells were easily visualized with cell-specific MRM.
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